Our Services
We don’t just test compounds; we predict their success through mitochondrial intelligence. And because your question is unique, our solutions are tailored to fit your needs.
Pharmaceutical Testing
Accelerate drug discovery with efficient, cost-effective efficacy and safety testing, supporting your project from R&D through pre-clinical testing.
Fast-fail Strategy
Early mitochondrial profiling to identify liabilities quickly.
Mechanism of action
Characterize a drug’s action by analyzing mitochondrial pathways.
Cancer
Target mitochondrial metabolism to overcome drug resistance.
CNS Diseases
Protect neurons by tracking mitochondrial function and quality.
Metabolic Diseases
Evaluate energy and ROS balance in metabolic disorders.
Anti-virals
Assess mitochondrial pathways to track antiviral efficacy and host response.
Cardioprotection
Monitor mitochondrial energy for heart health and cardio-toxicity insights.
Anti-virals
Assess mitochondrial pathways to track antiviral efficacy and host response.
Mitochondria sit at the core of innate antiviral immunity, with pathways like MAVS signaling directly influencing viral response and interferon activation. Measuring mitochondrial function and mtDNA stress provides a powerful way to assess both antiviral efficacy and potential host toxicity.
Key assays: mtDNA content, quantitative western blot analyses, Bioenergetic Balance Screen (BBS)+ package, and redox status.
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Cancer
Target mitochondrial metabolism to overcome drug resistance.
Cancer cells rely on altered mitochondrial metabolism and dynamics to sustain growth, resist apoptosis, and adapt to hypoxic environments. Targeting mitochondrial bioenergetics offers a strategic lever to overcome drug resistance and improve therapeutic outcomes.
Key assays: Mitoread Cancer Profiler and mtDNA content.
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Cardioprotection
Monitor mitochondrial energy for heart health and cardio-toxicity insights.
Cardiac function depends on tightly regulated mitochondrial energy production and quality control. Evaluating mitochondrial respiration, dynamics, and turnover enables early detection of cardiotoxicity and identification of protective mechanisms.
Key assays: mtDNA content and quality control, Bioenergetic Balance Screen (BBS) or BBS+ package, and redox status.
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Central Nervous System (CNS) diseases
Protect neurons by tracking mitochondrial function and quality.
Neuronal survival and function are critically dependent on mitochondrial energy supply, trafficking, and quality control. Subtle mitochondrial dysfunction can drive neurodegeneration, making it a key target for disease-modifying strategies.
Key assays: Mitoselect, mtDNA content and quality control, Bioenergetic Balance Screen (BBS) or BBS+ package, and redox status.
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Metabolic diseases
Evaluate energy and ROS balance in metabolic disorders.
Mitochondrial dysfunction is a central driver of metabolic disorders, impacting energy production, ROS balance, and insulin signaling. Targeting mitochondrial pathways enables a deeper understanding of disease mechanisms and therapeutic opportunities.
Key assays: Bioenergetic Balance Screen (BBS) or BBS+ package, redox status, mtDNA content and quality control, and mitochondrial membrane permeability assay.
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Fast-fail strategy
Early mitochondrial profiling to identify liabilities quickly.
Undetected mitochondrial liabilities are a leading cause of late-stage drug failure. Early mitochondrial profiling enables faster, data-driven decisions—reducing development costs and significantly improving pipeline ROI.
Key assays: Cellesis toxicity profiler, cellulomic and proteomic platforms, Bioenergetic Balance Screen (BBS) or BBS+ package.
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Mechanism of Action
Characterize a drug’s action by analyzing mitochondrial pathways.
Mitochondria integrate multiple cellular pathways, making them a powerful lens to uncover a drug’s true mechanism of action. Early mitochondrial insights accelerate lead optimization and refine indication strategies.
Key assays: Bioenergetic Balance Screen (BBS)+ package, redox status, mtDNA content and quality control.
Read Full DetailsCosmetics Testing
Support your R&D from early active ingredient screening to mechanistic validation, providing robust claim substantiation for your products.
Anti-aging
Reveal mitochondrial drivers of skin aging and longevity.
Anti-oxidation
Substantiate antioxidant effects through mitochondrial ROS control.
Sun protection
Demonstrate mitochondrial resilience to UV- and IR-induced stress.
Urban pollutants
Identify protection against pollution-driven mitochondrial damage.
Energizing
Demonstrate enhanced cellular energy through mitochondrial efficiency.
Slimming & Toning
Assess mitochondrial impact on fat metabolism and skin firmness.
Anti-aging
Reveal mitochondrial drivers of skin aging and longevity.
Mitochondria sit at the heart of skin aging, driving oxidative stress, inflammation, and cellular damage. Targeting mitochondrial function enables precise evaluation of your ingredients’ ability to prevent or even reverse age-related skin alterations.
Key assays: mtDNA content, Bioenergetic Balance Screen (BBS) or BBS+ package, and redox status.
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Anti-oxidation
Substantiate antioxidant effects through mitochondrial ROS control.
As the primary source and regulator of ROS, mitochondria control the balance between cellular signaling and oxidative damage. Measuring mitochondrial responses provides a robust, biologically relevant way to substantiate antioxidant claims.
Key assays: Redox status.
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Sun protection (Photo-protection)
Demonstrate mitochondrial resilience to UV- and IR-induced stress.
UV and infrared exposure directly disrupt mitochondrial function, accelerating photo-aging and cellular damage. Assessing mitochondrial resilience under controlled irradiation reveals the true protective potential of your active ingredients.
Key assays: Redox status, mtDNA content, and Bioenergetic Balance Screen (BBS) or BBS+ package.
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Protection from urban pollutants
Identify protection against pollution-driven mitochondrial damage.
Urban pollutants impair mitochondrial function and accelerate skin aging, especially in mature skin with reduced adaptive capacity. Evaluating mitochondrial health offers a sensitive and differentiated way to demonstrate protection against pollution-induced damage.
Key assays: Bioenergetic Balance Screen (BBS) or BBS+ package, mitochondrial dynamics, mitochondrial membrane potential (MMP).
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Energizing
Demonstrate enhanced cellular energy through mitochondrial efficiency.
Mitochondria are the cell’s energy engine, but true energizing effects go beyond ATP levels alone. Measuring mitochondrial respiration and metabolic efficiency provides a more accurate and meaningful assessment of cellular energy enhancement.
Key assays: Bioenergetic Balance Screen (BBS) or BBS+ package and BBS- Screening.
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Slimming & Toning (Firmness)
Assess mitochondrial impact on fat metabolism and skin firmness.
Mitochondria regulate key pathways in fat metabolism, thermogenesis, and collagen production, which are all central to body contouring and skin slimming. Targeting mitochondrial activity enables advanced claims around slimming, toning, and anti-cellulite effects.
Key assays: Bioenergetic Balance Screen (BBS) combined with quantitative western blot analysis, and redox status.
Read Full DetailsAI Model Co-Development
Leverage mitochondrial and cellular assay data to build predictive AI models that guide drug discovery, cosmetic screening, and biomarker development.
What We Do
We collaborate with your team to co-develop AI models using high-quality biological datasets. Whether you need datasets generated from scratch, expert review of your existing data, or advanced interpretation of cellular responses, we help turn complex biological signals into actionable predictions.
How It Works
- We generate or curate robust datasets from mitochondrial and cellular assays.
- Our experts analyze biological signals to provide actionable insights for AI model development.
- We support your AI team by offering guidance, annotations, and data that help train predictive models effectively.
- We collaborate closely with your team throughout development to ensure models are scientifically grounded and fit for purpose.
Applications
- Compound screening and prioritization
- Toxicity and safety prediction
- Efficacy ranking and lead optimization
- Biomarker discovery and patient stratification
- Diagnostics and predictive insights
Why mitochondrial data?
Mitochondrial readouts capture early, quantitative biological signals that are highly predictive. By integrating these insights into AI modeling, your team can build models that are both robust and biologically relevant to accelerate decision-making with confidence.
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